Reduce wrinkles associated with skin aging

• In 2007 Archives of Dermatology published a double-blind study in which 36 elderly subjects received treatment with .4 percent retinol (vitamin A) on one arm and its vehicle (control) on the other arm up to 3 times per week for 24 weeks.  Results showed that topical retinol improved fine wrinkles associated with aging, likely through increased skin hydration and collagen production.

Sinusitis

• In 2007 Acta Oto-laryngologica published an animal study which found that rabbits that were infected with sinusitis had better outcomes when treated with antibiotics with vitamin A, compared to antibiotics alone. Vitamin A increased antioxidant activity which improved tissue damage caused by free radicals, which is not addressed by antibiotics alone.

Low vitamin A and asthma

• In 2002 Pediatric Allergy and Immunology published a study based on 35 asthmatic children and 29 controls which found an association between low vitamin A levels and children with asthma. Additionally, children with the most severe asthma had the lowest vitamin A levels among the sample tested.

Constitutionally delayed children

• In 2004 Clinical Endocrinology published a study which found that, in a sample of 102 constitutionally delayed boys, 6 months of vitamin A and iron supplementation was as effective as oxandrolone and testosterone in inducing puberty.

Improved immune function in vitamin A deficient children

• In 2010 the International Journal for Vitamin and Nutrition Research published a study in which 52 children who were deficient in vitamin A saw increases in immune cell counts after being treated with 200,000 IU vitamin A for 2 months.

Acne – Vitamins A, E and Zinc

• In 2014 Cutaneous and Ocular Toxicology published a study which found that compared to a control group of 56 subjects,  a group of 94 acne patients had significantly lower levels of vitamin E, vitamin A and zinc.

Acne – Vitamin A and Vitamin E

• In 2006 Clinical and Experimental Dermatology published a study based on 100 acne patients and 100 controls which found a strong relationship between low vitamin A and E levels and increased acne severity. Additionally, those with the most severe acne had the lowest vitamin A and E levels.

Acne – Low-dose Vitamin A

• In 2015 Medical Archives published a study which found that 3 months treatment with 20 mg/day isotretinoin (vitamin A derivative) was effective in the treatment of moderate acne in 47 patients, with low incidence of side effects – with good results observed in 90 percent of patients.