Kidney Toxicity
- In 2006 Transnational Oncogenomics published an animal study which found that rats exposed to 400 ppm (parts per million) potassium bromate in their drinking water for 100 weeks had an increased likelihood of tumor growth in their kidney tissue. [Source]
- In 2012 Food Chemistry published an animal study which found that rats given a single dose of 100mg/kg body weight potassium bromate had a decline in kidney function and an increase in oxidative stress in the kidneys. The effects appeared to be reversible in many cases after 168 hours. [Source]
Liver and Kidney toxicity
- In 2009 Food and Chemical Toxicology published an animal study which indicated adverse effects on the kidneys and livers of rats fed a diet containing potassium bromate for 30 days. [Source]
Oxidative damage (pro-oxidant)
- In 2014 Environmental Toxicology published an in vitro study which found that red blood cells incubated with different doses of potassium bromate were ruptured or destroyed in a dose-dependent manner. According to the researchers, this result demonstrates that potassium bromate induces oxidative stress in human erythrocytes (red blood cells). [Source]
- In 2012 Chemosphere published an in vitro study which found that blood collected from rats and exposed to potassium bromate showed increased lipid peroxidation (oxidative damage) and decreased antioxidant levels. [Source]
Thrombocytopenia (deficiency of platelets in the blood)
- In 2009 the Nigerian Journal of Physiological Sciences published a study which found that the blood platelet counts of rats were significantly reduced (thrombocytopenia) when fed a potassium bromate solution for a 6-week period. The authors note that potassium bromate may be injurious to human health if consumed continuously and in high quantity. [Source]