Gluten-Free Diet

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  • In 2016 Clinical Gastroenterology and Hepatology published a study which found that 29 of 41 patients with IBS saw a significant reduction (greater than 50 reduction in severity) in symptom severity after 6 weeks on a gluten-free diet. [Source]
  • In 2014 Inflammatory Bowel Diseases published a study based on a gluten-free diet questionnaire of 1,647 patients with inflammatory bowel disease. Overall, 65 percent of patients who attempted a gluten-free diet saw an improvement in gastrointestinal symptoms, with 38 percent reporting fewer or less severe IBD flares. [Source]
  • In 2013 Gastroenterology published a 4-week trial which compared a gluten-free diet to a gluten-containing diet in IBS subjects with negative and positive HLA-DQ2 and HLA-DQ8 genes (genes which are associated with celiac disease). The researchers found that those individuals that tested positive for the genes were negatively affected by a gluten containing diet. [Source]

Quality of Life

  • In 2002 Effective Clinical Practice published a study in which 40 patients with celiac disease adhered to a gluten-free diet for one year. The diet was associated with an improved quality of life and improvements in gastrointestinal symptoms. [Source]

Altered Gut Microbiome

  • In 2016 Genome Medicine published a study which tracked the changes of the gut microbiome in 21 healthy volunteers who followed a gluten-free diet for 4 weeks. The gluten-free diet lead to significant changes in gut microbiome composition. [Source]


  • In 2016 World Journal of Pediatrics published a clinical trial in which 80 children with autism were assigned to either a gluten-free diet (GFD) or a regular diet for 6 weeks. The children in the GFD group saw a significant decrease in gastrointestinal symptoms and behavioral disorders compared to the children on the regular diet group. [Source]

Type 1 Diabetes

  • In 2012 the British Medical Journal published a case study in which a 6-year old boy with type 1 diabetes saw improvement in his condition after remaining on a gluten-free diet. [Source]

Increased risk for emotional and behavioral problems

  • In 2011 the British Medical Journal published a study which found that 100 children with celiac disease (who were treated and compliant) had a higher rate of emotional and behavioral problems than 100 healthy children in a control group. The authors note that the results highlight the importance of early detection of mental problems in children with celiac disease. [Source]

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