CLA (Conjugated Linoleic Acid)

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Reduced Body Fat

In 2007 the American Journal of Clinical Nutrition published a meta-analysis of 18 studies on CLA which concluded that 3.2 grams of CLA per day can lead to a modest reduction in body fat. [Source]
In 2004 the American Journal of Clinical Nutrition published a one year double-blind, placebo-controlled study to assess the effects of CLA on 180 healthy, overweight adults. The researchers concluded that long-term supplementation with CLA can reduce body fat mass in overweight individuals. [Source]
In 2007 the International Journal of Obesity published a double-blind, placebo-controlled trial involving 40 healthy, overweight adults. Results showed that 3.2 grams/day CLA produced a significant reduction in body fat over a 6-month supplementation period, while also preventing weight gain during the holiday season. [Source]
In 2012 Nutrition published a double-blind study comparing the effects of 12 weeks CLA supplementation with a placebo in 33 overweight subjects. Individuals with a BMI (Body mass index) of over 27 in the CLA group saw a reduction in fat mass, waist-to-hip ratio and body weight. [Source]
In 2001 The Journal of International Medical Research published a double-blind, placebo-controlled study of 20 participants, which found that individuals who exercised for 90 min, 3 times weekly and took .6 grams of CLA 3 times daily at meals lost significantly more body-fat in a 12-week period than individuals who exercised 3 times weekly and took a placebo. [Source]

In 2016 The British Journal of Nutrition published a meta-analysis of 170 studies comparing the nutritional profiles of organic and conventional cow’s milk. The data showed that organic milk was significantly higher in CLA as well as omega-3 fatty acids. The researchers concluded that organic milk has a more desirable fatty acid profile than conventional milk. [Source]
In 2009 The Journal of Dairy Research published a study comparing organic and conventional cow’s milk. The samples of organic milk all showed higher concentrations of CLA. The authors noted that the organic diet of the cows, which includes fresh or dried forage, appears to have the greatest effect on CLA concentrations. [Source]

In 2013 Breast Cancer Research and Treatment published a study which included women with stages I-III breast cancer in which the women took 7.5 grams of CLA per day before surgery. Results showed that 12 days of treatment with CLA lead to a reduction in the S14 gene – a gene over-expressed in mammary tumors. [Source]
In 2005 Experimental and Molecular Pathology published an in vitro study which showed that CLA posses properties which may inhibit the growth and spread of breast cancer cells. [Source]
In 2004 The Journal of Nutrition published an in vitro study in which CLA showed dose-dependent inhibition of breast cancer cell growth through its potent anti-estrogenic properties. [Source]
In 2016 Acta Poloniae Pharmaceutica published an animal study which showed that treatment with CLA reduced chemically-induced mammary tumors in female rats. [Source]
In 2007 Biochemical and Biophysical Research Communications published an in vitro study which demonstrated that components present in CLA supplements triggered mammary cancer cell death. [Source]

In 2016 Genes & Nutrition published an in vitro study which showed that CLA in organically produced eggs suppressed the expression of tumor cells. [Source]