Depression In 2013 ISRN Psychiatry published a double-blind, placebo-controlled trial in which 60 adults with major depression or other depressive disorders were assigned a B complex vitamin or a placebo. The B complex group saw significant improvements in depression, metal health and mood at 30- and 60-day follow-ups when compared to a placebo.
Reduce wrinkles associated with skin aging In 2007 Archives of Dermatology published a double-blind study in which 36 elderly subjects received treatment with .4 percent retinol (vitamin A) on one arm and its vehicle (control) on the other arm up to 3 times per week for 24 weeks. Results showed
Reduced common cold duration In 2013 The Cochrane Database of Systematic Reviews published a meta-analysis of 29 trials involving 11,306 participants which found that, while regular vitamin C supplementation could reduce the duration and severity of colds, it was not effective in preventing of the common cold. [Source] In 2006
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