- In 2013 The Indian Journal of Periodontology published a study involving 45 patients with plaque-induced gingivitis. Aloe vera mouthwash used twice daily for 3 months, used in combination with dental scaling, was able to reduce inflammation caused by gingivitis more than dental scaling alone.
- In 2011 the Journal of Indian Society of Periodontology published a study involving 15 subjects which found that intra-pocket placement of aloe vera gel done after scaling and root planing was effective in improving periodontal disease.
- In 2016 the Journal of Clinical and Diagnostic Research published an in vitro study which showed that aloe vera gel at 100 and 50 percent concentrations was effective against oral bacteria.
Erythema (skin redness)
- In 2014 Pharmacognosy Magazine published a study involving 63 subjects which found that aloe vera and aloe ferox gels reduced skin redness (arythema) similarly to hydrocortisone gel after 6 days of treatment.
Herpes simplex virus
- In 2016 the Journal of Dentistry published an in vitro study which showed that aloe vera gel could be a useful topical treatment for oral herpes simplex virus infections.
- In 2013 the Journal of Research in Medical Sciences published a study in which 33 patients with IBS consumed 30 ml (1/8 cup) of aloe vera juice twice daily for 8 weeks. Based on questionnaires, patients saw a significant reduction in abdominal pain and flatulence, with no change in stool urgency or frequency.
- In 2004 Ailmentary Pharmacology & Therapeutics published a double-blind study in which 44 patients were given either 100 ml (.4 cups) of aloe vera gel or a placebo twice daily for 4 weeks. Results showed aloe was more effective than a placebo in improving ulcerative colitis symptoms.
- In 2007 Burns published a review including 4 studies, totaling 371 patients which found that average burn healing time was 8.79 days shorter with aloe vera compared to controls.
- In 2013 The Journal of the Pakistan Medical Association published a study in which 50 patients in a hospital burn unit were divided into equal groups and were treated with either aloe vera gel or 1 percent silver sulfadiazine (SSD) cream. The patients in the aloe group saw remarkably faster healing and pain relief compared to patients in the SSD group.
Gastrointestinal disorders – Aloe with probiotics
- In 2012 Acta Bio-medica published an in vitro study which found evidence that aloe vera juice at a concentration of 5 percent can promote the growth of beneficial bacteria. Based on these findings the authors note the potential of aloe vera combined with probiotics in the treatment of gastrointestinal disorders.
- In 2009 Annals of Dermatology published a study in which 30 females over the age of 45 with photodamaged skin saw a significant reduction in facial wrinkles and improved skin elasticity as well as increased collagen production after 90 days of 1,200 or 3,600 mg/day dietary aloe vera gel supplementation – there was no difference seen between the different doses.
- In 2009 Phytotherapy Research published a study involving 30 patients which found that aloe vera gel was as effective as benzyl benzoate in the treatment of scabies.
- In 2003 the American Journal of Infection Control published a study in which assembly line workers with dry hands wore an aloe vera coated glove for 8hrs/day for 30 days. Noticeable improvement was seen after 3.5 days and marked improvement was seen after 10.4 days. Subjects saw improved skin integrity and reduced fine wrinkling.