• In 2010 Clinical and Experimental Ruematology published an article which detailed an account of a 50-year-old woman who suffered from fibromyalgia for more than 10 years. Upon removing aspartame from her diet she saw complete remission of symptoms. A 43-year old man saw similar results. The authors recommend an aspartame-free trial period for all fibromyalgia sufferers. [Source]


  • In 2012 Clinical and Experimental Rheumetology published a clinical trial in which 57 fibromyalgia sufferers were placed on diets excluding MSG and aspartame for 4 weeks. Of the 37 subjects who completed the trial, 84 percent reported that more than 30 percent of their symptoms were resolved. Subjects who improved were then randomized to a 2-week, double-blind, cross-over trial in which either MSG or a placebo was re-introduced into the diet 3 consecutive days a week. MSG reintroduction lead to a return of symptoms, worsening of fibromyalgia severity and decreased quality of life with regard to IBS symptoms. [Source]


  • In 2004 Arthritis Research and Therapy published a review which noted that psychological stress and the subsequent development of fibromyaglia are commonly associated with abnormal hormone levels in the body, specifically neuroendocrine function. [Source]

Chlorella Pyrenoidosa

  • In 2000 in Phototherapy Research published a pilot study in which 18 fibromyalgia patients consumed 10 grams chlorella tablets and 100 mL liquid chlorella daily for 2 months. Results showed that 7 patients felt that their symptoms improved, while 6 experienced no change and 5 believed their symptoms worsened.  [Source]
  • In 2001 Alternative Therapies in Health and Medicine published a double-blind clinical trial in which 55 patients with fibromyalgia, 33 with hypertension and 9 with ulcerative colitis (UC) consumed 10 grams chlorella tablets and 100 mL liquid chlorella daily for 2-3 months. Results showed that chlorella supplementation improved quality of life, blood pressure and UC symptoms for individuals with fibromyalgia, hypertension and ulcerative colitis, respectively. [Source]

Creatine Monohydrate

  • In 2013 Arthritis Care and Research published a double-blind trial in which 28 subjects received either creatine (20 g for first 5 days, 5 g for remainder of 16 weeks) or a placebo for 16 weeks. Results showed that creatine improved upper and lower body muscle function with no side effects reported. [Source]
  • In 2009 The Annals of the New York Academy of Sciences published a study which found that 8 weeks of  creatine supplementation produced a significant improvement in quality of life and sleep, disability, and pain in 30 fibromyalgia sufferers. Results deteriorated 4 weeks after stopping creatine therapy. [Source]

Vitamin D

  • In 2014 Pain published a study in which 30 women with fibromyalgia and low vitamin D levels were assigned to vitamin D or a placebo for 20 weeks. Results showed a marked reduction in pain in the vitamin D group. [Source]
  • In 2001 in the Journal of Rheuetotlogy published a which found that, in a group of 25 female fibromyaglia patients, half had low vitamin D levels. [Source]


  • In 2013 Redox Report published a study which showed that, in a sample of 10 juvenile fibromyalgia suffers, coenzyme Q10 levels were deficient. When 100 mg/day CoQ10 was supplemented for 12 weeks symptoms of chronic fatigue improved. [Source]
  • In 2013 Nutrition published a study in which 4 fibromyalgia sufferers were tested for CoQ10 levels – all were found to be deficient. After a treatment period with CoQ10 all 4 subjects saw clinical improvement. [Source]
  • In 2015 Antioxidants & Redox Signaling published a double-blind clinical trial in which 73 patients with chronic fatigue syndrome, (a disorder common in fibromyaglia patients) were treated with 200 mg/day CoQ10 plus 20 mg/day NADH or a placebo for 8 weeks. Compared to the placebo group the treatment group saw a significant improvement in fatigue. [Source]
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